The cochlea is the spiral-shaped structure within the inner ear responsible for our sense of hearing. To fully understand ...

Researchers from Leiden University Medical Center (LUMC) and the Leiden-based biotech company Ncardia have joined forces to ...

Article reviewed by Julía Crispim da Fontoura, a PhD candidate at the Federal University of Health Sciences of Porto Alegre, Brazil who uses organoids to study drug resistance. Stay up to date on the ...

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't ...

In a major leap forward for genetic and biomedical research, two scientists at the University of Missouri have developed a powerful new artificial intelligence tool that can predict the 3D shape of ...

Advancing neurological disorder research requires model systems that more accurately reflect the human brain. 3D cell cultures, such as organoids and spheroids, have emerged as game-changers by better ...

Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...

Most potential oncology drugs fail during the drug development pipeline, even when there has been promising data for their efficacy during the in vitro stage. This makes it vital to identify in vitro ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...