Plasmodium falciparum resistance to artemisinin derivatives, the first-line antimalarial drug, drives the search for new classes of chemotherapeutic agents. Current discovery is primarily directed ...

A safe and effective malaria vaccine is high on the wish list of most people concerned with global health. New results suggest how a leading vaccine candidate could be vastly improved. A safe and ...

A cocktail of AMA1 proteins of a few different strains can be effective in overcoming major limitations of earlier versions of AMA1 based malaria vaccine, a new study conducted by researchers, ...

A study could redefine part of the present lines of research toward a treatment against the parasites responsible for malaria and toxoplasmosis. This work, published on 10th October on the website of ...

Writing in Cell Reports, researchers from the National Institute of Allergy and Infectious Diseases (NIAID) and collaborators have presented a multifaceted analysis and structure-function study of a ...

Blood-stage malaria vaccines are intended to prevent clinical disease. The malaria vaccine FMP2.1/AS02 A, a recombinant protein based on apical membrane antigen 1 (AMA1) from the 3D7 strain of ...

A safe and effective malaria vaccine is high on the wish list of most people concerned with global health. Results published on December 26 in PLOS Pathogens suggest how a leading vaccine candidate ...

This work, published on 10th October on the website of Nature Communications, concerns the role of one protein which is common to these parasites. Called AMA1, it has been at the heart of many years' ...