The overexpression of the MYC oncogene could be explained through a new pathway that would act before transcription, when MYC binds to DNA. A group of scientists from Spain have identified how the ...

Metronomic methotrexate and cyclophosphamide after carboplatin included adjuvant chemotherapy in triple-negative breast cancer: A phase III study. This is an ASCO Meeting Abstract from the 2015 ASCO ...

Figure 5. miR-377 transfection in prostate cancer cell lines can target MYC 3′UTR, degrade its mRNA, and affect apoptosis, cell cycle, migration, and cell proliferation. “Our research findings suggest ...

Scientists from Stanford University and the University of Texas MD Anderson Cancer Center have discovered a class of molecules that use endogenous proteins to modulate genetic pathways involved in ...

The Myc family of transcription factors, including Myc, N-Myc, and L-Myc, bind DNA at specific sequences and regulate gene expression by binding to enhancer-box (E-Box) sequences via dimerization with ...

Phase II trial report of preoperative chemotherapy (CX) with S-1 plus cisplatin for stage IV gastric cancer (StIV GC). Background: The prognosis varied among the patients with the same stage, ...

The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system.