Researchers know that ApoE4 and Trem2 can worsen neurodegeneration in mouse models of tauopathy. Do these proteins conspire to exacerbate pathology? It turns out that ApoE4 causes much of the damage ...

Compared to the vast majority of the population carrying the more common E3 and E4 isoforms of ApoE, the few who have an ApoE2 allele enjoy reduced risk of late-onset Alzheimer’s disease. Now, a new ...

BIRMINGHAM, Ala. – Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain. The ...

In a new study, researchers have discovered a connection between inflammation in the areas of interstitial fibrosis and tubular atrophy (IFTA).

Autoimmune gastritis is a chronic progressive inflammatory condition that results in the replacement of the parietal cell mass by atrophic and metaplastic mucosa. A complex interaction of ...

Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain. The resulting ...

Frontotemporal lobar degeneration (FTLD) encompasses a group of diseases characterized by neuronal loss and gliosis of the frontal and temporal lobes. Almost all cases of FTLD can be classified into ...

Muscle atrophy is the loss of muscle mass. Low physical activity, nutritional deficiencies, genetic factors, and some medical conditions may contribute. Muscle atrophy due to inactivity can occur if a ...

Distinct retinal vessel atrophy patterns may be associated with multiple sclerosis (MS), but further research is needed to assess retinal vessel changes and their underlying role in MS. Changes in the ...

Testicular atrophy occurs when the testes shrink. Several potential causes include aging, underlying medical conditions, or infections. The testes are two reproductive glands located in the scrotum ...

BUFFALO, N.Y. — Neurodegeneration results from a number of neurological conditions affecting older adults, including Alzheimer’s disease and Parkinson’s disease. Treating such diseases is challenging ...

Testicular atrophy can occur due to inflammation caused by viral or bacterial infections, age, and injury, among other causes. Treatment can depend on the underlying cause. Testicular atrophy refers ...