Cadherin-17, also called liver-intestine cadherin, is a calcium-dependent transmembrane glycoprotein that mediates cell–cell adhesion in intestinal epithelium. Expression of cadherin-17 was reported ...

E-cadherin behaves like a glue in healthy tissues, keeping epithelial cells connected and organized. Discovered 43 years ago, this transmembrane glycoprotein connects epithelial cells together at ...

Fruit-fly ovaries were used in a new study to uncover how E-cadherin guides collective cell migration. According to traditional scientific dogma, E-cadherin acts like the mortar between bricks, ...

Researchers have comprehensively described the network of proteins involved in cell-cell adhesions, or the cadherin interactome. Many biological processes depend on the ability of cells to stick to ...

Preliminary results from a first-in-human phase 1 dose escalation trial of ADRX-0706, a next generation Nectin-4 ADC, in subjects with advanced solid tumors. Safety and efficacy data of study ...

E-cadherin, a member of the cadherin family, has a very important role in organizing the epithelium. Most cancers arise from epithelial tissue, and in those cancers, cell adhesion mediated by ...

P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...

Northeastern University scientists have discovered that a protein in the human brain could potentially be used to grow new neurons in the lab and enhance brain processes affected by aging or ...

Outcome of High-Risk Stage IC, Grade 3, Compared With Stage I Endometrial Carcinoma Patients: The Postoperative Radiation Therapy in Endometrial Carcinoma Trial Reduced tumor cell adhesion is ...

The paper A. Sing et al., “The atypical cadherin Fat directly regulates mitochondrial function and metabolic state,” Cell, 158:1293-1308, 2014. When clustered together in tissues, cells sense and ...