Cells have to invest a lot of energy to maintain this concentration gradient, especially when it comes to getting rid of calcium. 'It's like being on a rush-hour train in a city like Tokyo. When the ...

P-type ion transporting ATPases are ATP-powered ion pumps that establish ion concentration gradients across biological membranes. Transfer of bound cations to the lumenal or extracellular side occurs ...

Biochemists have uncovered the structure of cellular mechanism tied to thought, movement and other bodily functions. New atomic scale images of the structure of calcium's gatekeeper, IP3R, could go a ...

The process of energy generation by mitochondria is closely tied to intracellular calcium regulation by a membrane gateway inside mitochondria known as the mitochondrial Ca2+ uniporter (MCU). How MCU ...

Proton pumps in the membrane surrounding plant and yeast cells maintain the intracellular pH. The resulting membrane potential drives the uptake of other ions and nutrients. Hence, the proper function ...

The first comprehensive transport model of a plasma membrane calcium pump explains its high speed and opens up new avenues for drug development 'Drink your milk and you will have strong bones and ...