Inflammation plays a critical role in both acute and long term SARS-CoV-2 infection, as well as many of the most serious chronic diseases, such as Alzheimer’s, type 2 diabetes, and atherosclerosis.

A new study offers important mechanistic insights into a recently discovered CRISPR-guided caspase, or Craspase. Using cryo-electron microscopy (cryo-EM), researchers explained its target RNA cleavage ...

Caspase proteins play a critical role in programmed cell death, and they can spur the immune system to fight off disease. But humans don't have a single caspase that can fulfill the functions needed ...

Scientists have discovered that blocking a key cellular enzyme thought to protect against fatty liver disease may instead increase the risk of chronic liver damage and cancer as we age. In a major new ...