T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

In preliminary experiments with mice and lab-grown cells, Johns Hopkins Kimmel Cancer Center scientists have found that a protein-signaling process accelerates the work of the gene most frequently ...

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial ...

(MEMPHIS, Tenn. – November 6, 2025) The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s “tail” called phosphorylation patterns.

A lipid hidden within cells called phosphatidylserine reveals how the body initiates the removal of threats and cellular debris.

Researchers have identified a specific hormone produced by pancreatic beta cells as a direct driver of obesity-linked pancreatic cancer in mouse models, shifting scientific attention away from insulin ...

As inflamed regions of the gut form scar tissue, the space within the gut lumen becomes smaller and more restricted, leading ...