In every organism, the regulation of cell populations is a constant process. This balance relies on a continuous interplay ...

Mitochondria are central hubs for cellular stress adaptation, with their function integrated with both apoptosis and autophagy pathways that determine cell fate. Alterations in mitochondrial ...

High concentrations of free fatty acid (FFA) in ketotic dairy cows activate endoplasmic reticulum (ER) stress pathways, ...

Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in tumor cells. However, tumor cells have the ability to develop strategies to escape apoptosis, rendering the ...

Apoptosis, or programmed cell death, is a tightly regulated biological process necessary for normal tissue maintenance and development. However, aberrations in apoptotic signaling networks are ...

In the fight against disease, programmed cell death – also known as apoptosis – is a key protective function of the body. It breaks down cells that are damaged or have undergone dangerous changes.

A hallmark of type 2 diabetes is the progressive loss of beta cell mass: cells in the pancreas that produce and release ...