Jamil Saad, Ph.D. Jamil Saad, Ph.D., professor in the Department of Microbiology, is the latest winner of the Heersink School of Medicine’s Featured Discovery. This initiative celebrates important ...
Researchers from the California Institute of Technology and collaborating institutions have developed a novel HIV vaccine candidate, a new germline-targeting Env SOSIP trimer called 3nv.2, that is ...
When some viruses infect our bodies, “our immune system can create a type of ‘permanent immunity’, meaning that once you’ve been exposed to that virus, you’ve got protection from it and are typically ...
Two patients have received infusions of an investigational chimeric antigen receptor (CAR) T cell that targets the human immunodeficiency virus (HIV) envelope glycoprotein gp120 (LVgp120duoCAR-T cells ...
As the HIV virus glides up outside a human cell to dock and possibly inject its deadly cargo of genetic code, there’s a spectacularly brief moment in which a tiny piece of its surface snaps open to ...
Some HIV-1 carriers who have received an early antiretroviral treatment during several years are able to control the virus for a long term after treatment interruption. However, the mechanisms ...
Left: Structure of the Human Immunodeficiency Virus (HIV). Note the envelope protein that protects the virus against immunological detection and the small genome consisting of two short strands of RNA ...
The battle against HIV-1, the virus that causes AIDS, has been ongoing for decades. Perhaps one of the most important advances in their understanding and fight against the virus has been the ...
In order for HIV to replicate, the viral genome must enter into the cell nucleus and integrate into the host cell chromosome. Previous work suggests that the entry proceeds through nuclear pore ...
A team at the La Jolla Institute for Immunology has achieved a landmark breakthrough by unveiling the first three-dimensional structure of a viral protein deeply embedded in our DNA. Using ...
A study published in PNAS Microbiology found that enveloped viruses harbor greater cross-species transmissibility and are more likely to cause zoonotic infections than nonenveloped viruses. The ...
Left: Structure of the Human Immunodeficiency Virus (HIV). Note the envelope protein that protects the virus against immunological detection and the small genome consisting of two short strands of RNA ...
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