A novel, single tube, multi-parameter 7-color immunophenotyping assay was developed to characterize PNH clones in blood leukocytes. Monocytes, eosinophils and basophils had the highest proportion of ...

Ilene C. Wetiz, MD, professor of clinical medicine at the Keck School of Medicine at the University of Southern California, discusses the baseline characteristics of the case: "Our second case is how ...

Flow cytometry is a single-cell analytical technique that uses fluorophore-labeled cell structures or biomarkers to differentiate between cell populations. Through this method, researchers detect the ...

Flow cytometry is a way to look closely at the features of cells or particles. A sample of blood or tissue goes into a machine called a cytometer. In less than a minute, a computer can analyze ...

Around the same time, Mack Fulwyler, an engineer working at Los Alamos National Laboratory, needed to separate particles, so he drew on existing techniques to create droplets to separate cells from a ...

These findings suggest that clone size at PNH onset may serve as a prognostic factor for disease burden and MAVEs/TEs, aiding in clinical decision-making about treatment initiation or maintenance. In ...

This technology has vast potential to help patients but remains underutilized and underappreciated. The tools are there. What’s lacking are harmonized controls, regulatory guidelines and database ...

Flow cytometry is a powerful analytical tool used for high throughput particle or cell analysis, wherein the sample is passed in a single file through the incident light of a laser detector, allowing ...