Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...
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How major nuclear protein complexes control specialized gene regulation in cancer and beyond
Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...
Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...
Estrogen is known as an important hormone, and it can control many functions by regulating the activity of hundreds of genes.
We know the genes, but not their functions.” To resolve this long-standing bottleneck in microbial research, a joint research ...
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Jumping genes reshape cancer genomes through 3D chromatin interactions
Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.
The main text details the experimental design, including the generation of CO and CPO ADAMTS13 variants using different algorithms, and the evaluation of these variants in terms of protein expression, ...
Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...
Genetics is the study of genes and how they influence characteristics and health. Through a variety of technological methods, environmental factors, and lifestyle choices, it is possible to alter some ...
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