Dynamic light scattering is frequently utilized to assess the quality of protein aggregation, degradation and solution. However, for high-throughput screening, conventional dynamic light scattering ...
Fragment-based drug design (FBDD) has led to a revolution in contemporary drug discovery, facilitating a bottom-up approach to the identification and evolution of bioactive small molecules into viable ...
Nucleic acid-based therapeutics, including antisense oligonucleotides (ASO), small interfering RNA (siRNA), messenger RNA (mRNA), immunomodulatory DNA/RNA, and gene-editing guide RNA (gRNA), hold ...
Stay up to date on the latest science with Brush Up Summaries. What Is High Throughput Screening? High throughput screening, or HTS, is the automated testing of thousands to millions of biological, ...
Conventional high throughput screening for clinical candidates cannot evaluate over 99% of commercially available molecules, thereby restricting the accessible chemical search space for therapeutic ...
Stay up to date on the latest science with Brush Up Summaries. Article reviewed by Ninning Liu, PhD from the Wyss Institute at Harvard University. Similar to retail stores that use standardized ...
A review maps high throughput strategies that link automation, microfluidics, and barcoding into a unified pipeline, enabling faster, more predictive lipid nanoparticle development for genetic ...
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