Inflammation is triggered by the immune system and is part of the body’s natural response to injuries or disease. However, abnormal inflammation has recently been established as a hallmark for ...

Irvine, Calif., April 21, 2025 — A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer’s disease and other neurological disorders, according to ...

The Xu laboratory works on developing human stem cell models to study the underlying mechanisms of human neurological disorders, such as Alzheimer's disease, and apply these models for drug screening.

The blood-brain barrier border protects the brain by regulating the flow of molecules, peptides, and cells, but it also keeps out many therapeutics. Now, researchers have harnessed the power of a ...

For years, researchers considered Alzheimer’s disease (AD) an amyloid beta and neuron-related condition. But having trained as a pathologist, Thomas Montine, who is now a neuropathology researcher at ...

Researchers have identified that microglia first help spread Alzheimer’s disease pathology across the brain and then activate to limit its neurodegenerative effects. Researchers from the VIB-KU Leuven ...

Scientists broadly agree that both apolipoprotein E and microglia are necessary ingredients for amyloidosis. In mice devoid of ApoE, or of their microglia, scant plaques form. Now, a sweeping study ...