Acute myeloid leukemia (AML) impairs neutrophil maturation in bone marrow, with mature neutrophils decreasing by over 78% in marrow and 89% in blood. AML-exposed neutrophils acquire inflammatory ...

Clarivate plc has unveiled the 2025 Citation Laureates. Widely considered a predictor of the Nobel Prizes, this recognition has highlighted the discovery of biomolecular condensates in chemistry and ...

Survivors of common lymphoid neoplasms (LNs) have increased risks for therapy-related myelodysplastic syndrome/acute myeloid leukemia (tMDS/AML), although risks have been lower in more recent years, ...

A research team at Lund University in Sweden has discovered a mechanism that helps acute myeloid leukemia cells to evade the body's immune system. By developing an antibody that blocks the mechanism, ...

A Yale study published on the cover of the journal Blood explains basic scientific discoveries that could lead to innovative therapies for acute myeloid leukemia, and specifically a rare and ...

Different pathways within the cell are activated or silenced dependent on the external signals acting on a cell. One such pathway includes the stimulator of interferon genes (STING) pathway which acts ...

The diagram depicts negative feedback mechanisms via IκB proteins and A20 in the canonical pathway, and IKKα onto NIK in the non-canonical pathway. There are cross-talk mechanisms such as NIK ...