Protein evolution occurs slowly via small incremental mutations—usually. However, dramatic changes can happen: for instance, a fragment of one protein getting copied into the middle of another. While ...

The tissue in our body can only hold together if the cells adhere not only to each other, but also to extracellular structures, such as collagen fibres of the connective tissue and the skin. How ...

“Cell migration is required and essential for metazoan development, tissue regeneration and repair, as well as in immune surveillance. Many diseases such as cancer, fibrosis, and inherited ...

Researchers from the US and China summarize the role of integrins in cancer cells and the current status of anti-integrin therapy for cancer Globally, human hepatocellular carcinoma (HCC) is the sixth ...

In a recent study published in the Proceedings of the National Academy of Sciences Journal, researchers examined the therapeutic effects of targeting integrins for treating Amyotrophic lateral ...

Research teams are analyzing how proteins work together to enable our cells to both stick and move. The marker protein paxillin is at the center of their interest. The tissue in our body can only hold ...