BACKGROUND: Genetic variants in components or regulators of the RAS-MAPK signaling pathway are causative for severe and early-onset hypertrophic cardiomyopathy (HCM) in patients with Noonan syndrome ...
Glioblastoma (GBM) is a fast-growing and currently incurable brain cancer, and the most common malignant brain tumor in adults. Standard treatment includes surgery to remove the tumor followed by ...
Mechanosensitive recruitment of DLC1 to focal adhesions creates a positive feedback loop that locally amplifies Rho activation in response to tension.
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