Unlocking the therapeutic applicability of LNP-mRNA: chemistry, formulation, and clinical strategies
LNP as the novel drug delivery system enhancing mRNA therapeutic efficacy has been proved for its delivery ability. This review provides valuable insights into the current state-of-the-art of LNP mRNA ...
Fig. 2 Examples of ionizable lipids, sterols, phospholipids, and PEG-lipids used in LNP formulations. Created with BioRender.com. Fig. 3 High-throughput screening of the 3-component ionizable ...
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