Inspired by hepatic lobules, a novel artificial liver was developed by assembling morphological cell sheets with high accuracy in terms of cell type, density, and distribution. By simulating the ...

The central vein (CV) region, driven by the Wnt signaling pathway, and the portal vein (PV) region, driven by the Notch signaling pathway, enable us to construct a biomimetic liver lobule ...

Resection of tumors in the caudate lobe (a deep, hard-to-reach part of the liver) is recognized as one of the most ...