Lysosomes, often reductively referred to as the "garbage disposals" of cells, play a pivotal role in our cells' digestive systems by getting rid of unwanted materials. Now in a groundbreaking study, ...

Researchers have revealed the structure and function of a previously unknown lysosome transporter. The groups of Christian Löw (CSSB, EMBL Hamburg), Markus Damme (Christian-Albrechts-University Kiel), ...

Scientists have pinpointed a protein in lysosomes that is involved in recycling a crucial fatty component of cell membranes to keep cells healthy. Researchers at Duke-NUS Medical School and colleagues ...

Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes. An organelle is a small structure in a cell that is ...

In LSDs, this accumulation also prompts STING to generate inflammation. Thus, finding a way to dampen STING's inflammatory role while encouraging its lysosome repair and generation role could offer a ...

In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed. In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, ...

Lysosomes require tight regulation of their pH to degrade their contents. Researchers know that V-ATPase pumps protons into these little digestive sacs, but what protein shuttles the ions back out?

Lysosomes are thought of as cellular organelles that play an important role in recycling proteins and maintaning cells by breaking down stuff that isn’t needed. But new research has found that ...

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in Nature Communications on how the targeted suppression of lysosome function may lead to brain cancer therapy.

To age or not to age! How does aging affect organisms on a cellular level? What mechanisms help cells survive self-inflicted or external harm? It is known that lysosomes - critically important ...