Advances in monoclonal antibody (mAb) technology have revolutionized the field of biological research. With applications in both research and therapeutics, mAb development is one of the fastest ...

Monoclonal antibodies (mAbs) are important biopharmaceuticals for the treatment of many diseases. During manufacturing the proteins tend to form aggregates, which reduce product yields, influence drug ...

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A therapeutic monoclonal antibody and its Fab and Fc fragments were recently investigated using differential scanning fluorimetry, temperature-ramped dynamic light scattering, and turbidity ...

The white paper presents three applications using multi-detector AF4 and EAF4: Separation and characterization of Adeno-Associated Virus (AAV) monomers and their fragments or aggregates; The ...

At-line process monitoring (ALPM) is a major application of ultra-high performance size-exclusion chromatography (UHP-SEC). ALPM of biological drugs helps to reduce the time and effort associated with ...

In 2012, BioPlan Associates estimated the global market for biopharmaceuticals at $140 billion, of which $100 billion was for recombinant proteins. The monoclonal antibody (mAb) market, a subclass of ...

The interaction of lymphocyte function-associated antigen-1 (LFA-1) with its ligands mediates multiple cell adhesion processes of capital importance during immune responses. We have obtained three ...