In neurodegenerative diseases, microglia can help or harm the brain. In the October 3 Journal of Clinical Investigation, scientists led by Ilia Baskakov at the University of Maryland School of ...
A clearance mechanism involving microglia has been known to relieve neurons of toxic protein aggregates such as those associated with Alzheimer’s disease and Parkinson’s disease. Unfortunately, this ...
Somewhere in the tangle of a brain under siege by Parkinson’s disease, immune cells appear to be doing something remarkable: ...
The brain contains many cell types, from the prominent neurons to the lesser-known microglia. The latter are integral to the brain's immune system and play a crucial role as the brain's cleanup crew.
Friend or foe? The debate about disease-associated microglia persists eight years after their discovery. If only there was a way to interrogate DAMs in living people and see how they correlate with ...
Scientists have uncovered a surprising overlap between cancer genetics and Alzheimer’s disease, involving mutations in the ...
A new Nature Genetics study has identified abnormal regulatory patterns in excitatory neurons and microglia linked to genetic risk for major depressive disorder. The findings suggest that depression’s ...
The central nervous system (CNS) encompasses the spinal cord and brain, which includes neurons and glia cells. The signaling cells of the CNS, neurons carry electrical imposes to neighboring neurons, ...