When a muscle contracts, the parts of a sarcomere "shorten" and come closer together. Each cardiac muscle cell can have over 5,000 sarcomeres, which compounds both the shortening and relaxation events ...

Researchers at the University of Cincinnati say a regulatory protein found in skeletal muscle fiber may play an important role in the body's fight or flight response when encountering stressful ...

Myosin chaperones are pivotal in ensuring proper muscle development by guiding the folding, assembly, and quality control of myosin motor proteins. These specialised proteins, such as UNC-45, ...

At the molecular level, muscle contraction is defined by myosin molecules pulling actin filaments. New electron cryomicroscopy images with unprecedented resolution taken by researchers at Osaka ...

The heart is the only muscle that contracts and relaxes continuously over a lifetime to pump oxygen-rich blood to the body's organs. Researchers at UT Southwestern Medical Center now have identified a ...

Smooth muscle cells use an actin-myosin II-based contractile apparatus to produce force for a variety of physiological functions, including blood pressure regulation and gut peristalsis. The ...

Living cells are highly organized, yet they are not assembled using rigid blueprints or by following a predetermined plan.

Understanding how microscopic interactions between proteins in cells produce large-scale organization and asymmetry is a fundamental question in cell biology.

The Journal of Cell Biology (JCB) is a not-for-profit publication, edited by scientists, and a leading life sciences journal. The JCB publishes papers on all aspects of cellular structure and function ...

Living cells are highly organized, yet they are not assembled using rigid blueprints or by following a predetermined plan. Instead, order emerges on ...