This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC ...

In an extensive review, researchers explore ZBP1-mediated programmed cell death and its potential as a therapeutic target for systemic diseases Programmed cell death, or PCD, is an actively regulated ...

Metacaspases, ancestral homologues of the caspase family, are pivotal cysteine proteases found in a wide range of unicellular organisms, including yeasts, algae, and phytoplankton. These enzymes ...

Under the microscope, it is possible to see for the first time how microalgae undergo the same type of programmed cell death as animal cells. (Microalga Guillardia theta in purple and apoptotic bodies ...

Plants form a critical model for understanding regulated cell death (RCD) as part of their sophisticated immune responses. In the ongoing evolutionary arms ...

There are several programmed cell death pathways that lead to cellular self-destruction, either for developmental processes, tissue maintenance, or stress responses. These include apoptosis, ...

How did cells evolve a process to end their own lives? Recent research suggests that apoptosis, a form of programmed cell death, first arose billions of years ago in bacteria with a primitive ...

Self-incompatibility (SI) is a genetically controlled mechanism that prevents self-fertilization and thus encourages outbreeding and genetic diversity. During pollination, most SI systems utilize cell ...

This finding, he suggests, helps link the study of cell death in the worm and oncogenesis in people. "There were a number of papers that had suggested a relationship between cell death and oncogenesis ...