A crucial ‘precursor’ has been identified in pathological protein fibril formation. Researchers from Tokyo Metropolitan University (Japan) have applied ideas from polymer physics to illuminate the ...

New evidence shows that precursors of myelin-producing cells — one of the few #brain cell types that continue to be produced ...

Researchers at ETH Zurich recently explained the role of a molecular complex that orchestrates the production of proteins in our cells. They now show that this complex also controls the processing of ...

Cerebrospinal fluid (CSF) is a clear and watery liquid that flows in and around the brain and spinal cord. Its functions include protecting parts of the nervous system, delivering nutrients and ...

Through protein structures obtained using cryo-electron microscopy, Chia-Hsueh Lee, PhD, St. Jude Department of Structural Biology demonstrated the role of the ‘pseudoprotease’ iRhom2 in regulating ...

Misfolded proteins can appear as small aggregates, soluble monomers, or large insoluble inclusion bodies. While the fundamental biophysical mechanisms that cause cytotoxicity are not fully understood, ...