The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...
Deaths from cancer or infections can occur when available treatments are ineffective. Once turned on, pregnane X receptor (PXR) activates the expression of genes encoding enzymes that metabolize ...
Corresponding author Taosheng Chen, PhD (left), co-first author Sergio Chai, PhD (center) and co-author Shyaron Poudel, St. Jude Department of Chemical Biology & Therapeutics investigated the ...
Pregnane X receptor (PXR) is a transcription factor that plays a crucial role in maintaining bile acid homeostasis by regulating major metabolizing enzymes and transporters.