British researchers report in today’s Science that they have managed to prevent and even reverse clinical manifestations of prion disease. Surprisingly, they did it not by eliminating deposits of ...

Infectious prions or PrPSc -- misfolded versions of the normal cellular prion protein PrPC -- convert their normal counterparts into copies of themselves and thereby cause fatal disease. How this ...

The neurological damage that comes with mad cow disease or other prion disorders could be reversible if caught early on, says a study from Giovanna Mallucci and John Collinge at the Institute of ...