RecBCD, an enzyme that unwinds the DNA double helix so that it can be copied or repaired, is powered by two motor units that run in opposite directions, according to a report by UC Davis researchers ...
A chance meeting in a hallway nearly 10 years ago has lead Stephen Kowalczykowski to new insights into the molecular machines that look after DNA. Now Kowalczykowski's colleagues have named him as the ...
The unwinding or 'unzipping' of duplex DNA to produce single-stranded DNA (ssDNA) is essential for all processes that involve a ssDNA template or reaction intermediate, including DNA replication, ...
When a break occurs in the DNA double helix, it must be dealt with rapidly. The structure of one of the cellular machines responsible is now revealed, offering insights into its impressive speed and ...
The DNA of all organisms, be it bacteria or humans, is constantly bombarded with damage either by environmental mutagens such as the exposure to UV light or because of erroneous replication. The ...
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