Ribosomal subunit assembly and biogenesis constitute a fundamental process vital for cellular protein synthesis across all domains of life. This complex, multi-step pathway involves the transcription ...
Mitochondrial ribosomal protein family in cancers: Mechanistic insights and therapeutic implications
(A) MRPS29 interacts with ADAR2 and represses A-to-I RNA editing by disrupting the association of ADAR2 with dsRNA, which induces the accumulation of PDZD7WT in cells to promote cancer. (B) MRPL9 ...
Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...
The ribosome serves as the essential molecular machine that translates genetic information carried by messenger RNA (mRNA) into functional proteins. Comprised of two distinct subunits, the ribosome ...
Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it ...
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Researchers discover how aggressive breast cancer controls protein production
A previously unknown mechanism that makes it possible for aggressive so-called triple-negative breast cancer to fine-tune its ...
A previously unknown mechanism that makes it possible for aggressive so-called triple-negative breast cancer to fine-tune its ...
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