Complement activation contributes to platelet destruction in immune thrombocytopenia (ITP). However, there has been very little data describing serum complement levels in ITP patients, and no data ...

Specificity of serum complement component to elicit immunological demyelination. Rats received intraspinal infusions of demyelinating reagents, delivered by osmotic minipump, for a 7-day infusion at 0 ...

Lentiviral vectors pseudotyped with G glycoprotein from vesicular stomatitis virus (VSV-G) and baculovirus gp64 are inactivated by human complement. The extent of vector inactivation in serum from ...

In view of the importance of complement system in the initiation, regulation and end effects of immune responses and understanding of immune system as one of the targets for the toxic effects of ...

CAMBRIDGE, Mass.--Alnylam Pharmaceuticals, Inc. (Nasdaq:ALNY), a leading RNAi therapeutics company, today announced initial positive results from its ongoing Phase 1/2 clinical trial with ALN-CC5, an ...

A team of investigators at the Medical University of South Carolina (MUSC) has developed a novel therapy for ischemic (clot-caused) stroke and has shown in a preclinical model that it locally inhibits ...

This is a preview. Log in through your library . Abstract Serum is an environment in which bacterial cells should not exist. The serum complement system provides innate defense against microbial ...