Mechanistic model for MTOC maturation in GV oocytes. The MTOC (grey) activates near the oocyte cortex, which requires recruitment of CKAP5 and TACC3. After activation, MTOC migrates to the nuclear ...
Numerous principles of chromosome recombination and cell cycle control have been illuminated by studying meiosis, the specialized cell division cycle in which mating-competent haploid gametes are ...