Speckles are dynamic subnuclear structures that contain pre-messenger RNA splicing factors and other proteins that are involved in transcription, 3′- end RNA-processing and reversible protein ...

To convert a gene into a protein, a cell first crafts a blueprint out of RNA. One of the main players in this process has been identified by researchers. The team "fished" a large complex of proteins ...

This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...

Nuclear speckles are non–membrane-bound organelles known as storage sites for messenger RNA (mRNA) processing and splicing factors. More recently, nuclear speckles have also been implicated in ...

To carry out all of life’s functions, proteins must be produced from instructions carried by genes within DNA and delivered to the cell’s protein-making machinery by messenger RNA. However, to ...

Researchers analyzed gene expression and network connectivity across eight human tissues and found shared aging-related ...