Stem cell-derived endothelial cell differentiation represents a rapidly advancing field that leverages the plasticity of pluripotent cells to generate functional vascular components. Central to the ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

The sugar glucose, which is the main source of energy in almost every living cell, has been revealed in a Stanford Medicine study to also be a master regulator of tissue differentiation - the process ...

A sweeping genetic screen reveals how the brain is built and exposes a hidden gene behind a newly discovered childhood brain ...

For the first time, researchers at the University of British Columbia have demonstrated how to reliably produce an important ...

A large genetic screen has revealed how stem cells transform into brain cells, exposing hundreds of genes that make this ...

The illustration depicts how during differentiation cells normally lose their plasticity and ability to acquire new fates. However, when fully differentiated B cells (naive B cells) initiate an immune ...