Tools for understanding the development, phenotype, and function of specific T cell subsets are critical to the modern immunologist. Tonbo Biosciences provides a rapidly expanding portfolio of ...

Naive CD4 cells are capable of integrating signals from antigen-activated cells of the innate immune system and differentiating into effector CD4 cells, also termed T helper (Th) cells. According to ...

The cytokine IL-9 promotes a multiple sclerosis-like disease in mice, according to a new study by Nowak et al. published online on July 13th in the Journal of Experimental Medicine. In a related ...

In this study, we aimed to analyze spatial organization of the single Ifng gene in functionally different Th cell subsets before and after activation in the context of nuclear matrix attachment ...

Ben-Gurion University of the Negev's Prof. Alon Monsonego had discovered that T helper lymphocytes, a subset of immune cells which regulate immunity, undergo functional changes with age. These changes ...

When T-cells are activated, naive CD4 + cells will differentiate into various types of T helper (Th) cells. One notable factor influencing this differentiation is the cytokine milieu present during ...

ABSTRACT Disease directly caused by immune system action is known as immunopathology. Many factors may lead the immune system to cause rather than cure disease, and autoimmune, allergic, and infection ...