Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

An international research team led by Professor Kiavash Movahedi from the Brussels Center for Immunology at the Vrije Universiteit Brussel has published unexpected results in the journal Immunity.

The BCG vaccine protects against tuberculosis, but by inducing trained immunity it also protects against many more respiratory infections. International research led by the Radboudumc shows how this ...

Exposure to a common fungal molecule can reprogram immune cells in the lungs, causing them to overreact to infection-like signals and worsen lung damage, according to new research. The study, ...

Scientists discovered that lowering a specific molecule helps microglia switch into a protective state that quiets brain inflammation in Alzheimer’s. A small group of these cells seems to have an ...

It’s hard to overstate how crucial microglia are to brain health. These humble immune cells quietly patrol the central nervous system, clearing debris, pruning synapses, and maintaining myelin. But ...

Researchers have identified a key role microglia play in the progression of melanoma brain metastases. A research team led by Berta Sanchez-Laorden at the Institute for Neurosciences (Alicante, Spain) ...

Replacing rogue microglia with healthy ones can ameliorate, in a mouse model, a childhood neurodegenerative disease called Globoid cell leukodystrophy (GLD), aka Krabbe disease. The approach even ...