A revolution has occurred in the field of pharmaceutical development due to the development of drugs that target membrane proteins. It is estimated that one-third of currently available drugs target G ...

In this interview, Dr. Fang-Yi Chu talks to NewsMedical about the role of transmembrane proteins in targeting oncology research. Can you explain what transmembrane proteins are and why they are ...

Transmembrane proteins (TPs) serve as crucial conduits between the internal and external environments of cells, regulating ion and molecule passage and orchestrating cellular responses to external ...

Zeno Management Inc. has identified antibody-drug conjugates comprising antibodies targeting inactive tyrosine-protein kinase transmembrane receptor ROR1 (ROR1) covalently bound to exatecan ...

Located at the cellular interface, membrane proteins play critical regulatory roles in the signaling between a cell and its interacting environment, making them popular and ideal drug targets.

Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results, researchers are now watching individual molecules collide with cell ...

Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...