Positive Phase 1 data confirm MP0317’s tumor-localized CD40 activation with a favorable safety profile in patients with advanced cancer ...
Lung cancer treatment and outcomes are profoundly influenced by the tumor microenvironment (TME), particularly in resectable ...
Glioblastoma remains a highly challenging malignancy with a pronounced tendency for recurrence. The hypoxic microenvironment ...
Johns Hopkins University cancer researcher Mikala Egeblad has received the 2025 Ernst W. Bertner Memorial Award in recognition of her research into how tumor microenvironments impact cancer ...
The field of lung cancer research has increasingly turned its attention to the tumor immune microenvironment (TIME) in non-small cell lung cancer (NSCLC), ...
TAMs upregulate CD36 and IL-1β induced MARCO to enhance the uptake of lipids (FAs, cholesterol, LDL) and EVs, driving LD biogenesis. This LD accumulation reinforces FAO and upregulates PI3K-γ, ...
TNX-1700 (TFF2-albumin fusion protein) reversed aging-associated gastric inflammation and significantly attenuated tumor progression in aged ...
Researchers at the University of Illinois Chicago have developed an anti-cancer therapy inspired by bacteria found in cancer ...
Prostate cancer (PCa) is one of the most common malignant tumors among men worldwide. Following androgen deprivation therapy (ADT), the disease often progresses to castration-resistant prostate cancer ...
New findings suggest that melanoma does not behave uniformly across the lifespan, with immune defenses and tumor activity ...
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