A vascularized organoid model of hormone-secreting cells in the pancreas has been developed, with potential to improve diabetes research and cell-based therapies. “Our results highlight the importance ...

For over a decade, scientists have been growing organoids—small clusters of cells that mimic a particular organ—to serve as miniature biological models. Organoids of the brain have been used to study ...

Until now, it has been difficult to maintain retinal ganglion cells deep inside organoids over extended periods. The supply of nutrients and oxygen in the densely packed tissues is limited, leading to ...

An international team of researchers led by Max Delbrück Center Scientific Director Professor Maike Sander, MD, has for the first time developed an organoid model of human pluripotent stem ...

Researchers have devised the right conditions to grow vascularized stem cell islets. The image shows vasculature (red) tightly wrapped around insulin-producing cells (green) in the islets (blue).

The development of cerebral organoids can offer opportunities to understand neurodevelopment and brain disease but faces several limitations, such as the lack of vasculature. In this study, ...

The bone marrow serves as the main site of hematopoiesis in humans, giving rise to red and white blood cells. This space is highly organized into distinct regions, or niches, that perform different ...

Typically, bone marrow research relies heavily on animal models and oversimplified cell cultures in the laboratory. Now, researchers from the Department of Biomedicine at the University of Basel and ...

For over a decade, scientists have been growing organoids - small clusters of cells that mimic a particular organ - to serve as miniature biological models. Organoids of the brain have been used to ...