Despite the fundamental nature of these events, organisms have evolved surprisingly divergent strategies that control replication onset. [2] Although the specific replication origin organization …

DNA synthesis of daughter strands starts at discrete sites, termed replication origins, and proceeds in a bidirectional manner until all genomic DNA is replicated. Despite the fundamental nature of these …

The origin of replication is defined as the specific location on a DNA molecule where DNA duplication begins, allowing for bidirectional replication. In eukaryotic chromosomes, multiple origins are spaced …

Aug 26, 2025 · An origin of replication is a specific DNA sequence where replication begins. It functions as a precise starting point, ensuring DNA synthesis does not occur randomly across the genome.

Origins of replication are specific sequences in the DNA where the process of DNA replication begins. These sites are critical for ensuring that the entire genome is accurately copied during cell division, …

DNA synthesis of daughter strands starts at discrete sites, termed replication origins, and proceeds in a bidirectional manner until all genomic DNA is replicated. Despite the fundamental nature of these …

Jul 26, 2025 · What is the Origin of Replication? The origin of replication is a specific DNA sequence within a genome where DNA replication begins. It serves as the starting point for synthesizing new …

In higher organisms, replication begins at multiple origins of replication and moves along the DNA in both directions outward from each origin, creating two replication “forks.”

Here we summarize recent advances in our understanding of how primary sequence, chromatin environment, and nuclear architecture contribute to the dynamic selection and activation of …

Within the genome are DNA sequences that encode functions (→), such as acting as an origin of replication or as a telomere. Prokaryotic (circular) chromosomes have a terminator (TER) region, …