The mTOR signaling pathway acts as a molecular systems integrator to support organismal and cellular interactions with the environment. The mTOR pathway regulates homeostasis by …

Dec 30, 2025 · The mammalian target of rapamycin (mTOR) pathway is a central regulator of cellular growth, metabolism, and homeostasis, integrating a wide array of intracellular and …

Aug 5, 2025 · Discover how mTOR, a fundamental cellular signaling pathway, governs cell growth, metabolism, and survival, profoundly influencing health.

4 days ago · Discover the mTOR pathway and its role in cellular growth and metabolism. Click here to explore the intricacies of this vital signaling pathway.

Regulation of Autophagy: mTOR plays a central role in regulating autophagy through two major signaling pathways, i.e., the AMPK-mTOR pathway and the PI3K-Akt-mTOR pathway.

Jul 23, 2025 · The mTOR signaling pathway, which is frequently activated in tumors, is crucial for tumor metabolism because it not only controls protein synthesis and gene transcription to …

Oct 1, 2023 · In this review, we summarize recent advances in understanding the structural mechanisms of how the mTOR pathway operates in the cell. For clarity, we refer to proteins …

The mammalian target of rapamycin (mTOR) protein, a member of the phosphoinositide 3-kinase (PI3K)-related protein kinase (PIKK) family, has a central role in two growth-regulatory …

What is mTOR signaling pathway? The mammalian target of rapamycin (mTOR) signaling pathway integrates both intracellular and extracellular signals and plays an important role in …

Jun 2, 2024 · Embedded in a complex network of signaling pathways, mTOR dysregulation is implicated in the onset and progression of a range of human diseases, including metabolic …