LC Troubleshooting | Retention Time Shift | 5 most common causes to change in retention time in HPLC
4:58
YouTubeEnglish Excel
LC Troubleshooting | Retention Time Shift | 5 most common causes to change in retention time in HPLC
Retention times must be reproducible from run to run. When problems occur, late, early or variable peak retention times may be observed. There are lots of potential causes to change in retention time. In this video I will discuss five most common causes why they may occur and what you can do to stabilize them: I hope these tips make it easier ...
30.8K viewsOct 15, 2020
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Modukuri Gopi on Instagram: "**"Relative Retention Time (RRT) in HPLC 1. Introduction High-Performance Liquid Chromatography (HPLC) is a widely used analytical technique in pharmaceutical, chemical and research laboratories. 2. What is Relative Retention Time (RRT)? Relative Retention Time (RRT) is the ratio of the retention time of an analyte or impurity peak to the retention time of a reference compound (usually the main drug substance peak), analyzed under the same chromatographic conditions.
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Modukuri Gopi on Instagram: "**"Relative Retention Time (RRT) in HPLC 1. Introduction High-Performance Liquid Chromatography (HPLC) is a widely used analytical technique in pharmaceutical, chemical and research laboratories. 2. What is Relative Retention Time (RRT)? Relative Retention Time (RRT) is the ratio of the retention time of an analyte or impurity peak to the retention time of a reference compound (usually the main drug substance peak), analyzed under the same chromatographic conditions.
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